Does anyone have any experience of DLI plus Nelarabine to treat early relapse?
My 18 year old daughter is 3 months post transplant; everything seemed to be going very well - discharged day 28, excellent blood counts, 100% chimerism. But we've just had the devastating news that she has relapsed. They've explained that the prognosis for such an early relapse is very poor and options are about buying time rather than finding a cure. From what I can see, she' likely to have only a few months without treatment. One option for trying to extend this is Nelarabine chemo plus DLI. Does anyone have experience of this? If successful, are we looking at months or years? She underwent two rounds of Fla-Ida prior to transplant which really knocked her for six; it involved weeks and weeks in hospital and a couple of transfers to intensive care. Would love to hear from anyone who's had DLI plus chemo and what the outcome was.